DeepZero | iPinYou reached potential customers who were frequent business and holiday travelers, as well as family segments, through interest-based targeting. By continuously re-engaging with customers who have previously searched or booked travel services, we optimized the campaign performance, resulting in a 2.3% increase in clickthrough rates and a remarkable 211% increase in flight bookings from China within 4 months. Our approach enables us to match 5 million mobile devices with OTT devices and deliver unskippable impressions at a scale of 132 million. Furthermore, we collect anonymous data across multiple devices to create profiles for retargeting with personalized creatives and sequential messaging.